Endocrine Abstracts

Introduction: Dysthyroidism is not uncommon during chromosomal aberrations. The objective of this work is to study the characteristics of this association at the epidemiological and clinical levels.Methods: This is a retrospective study of 27 cases of patients with trisomy 21 chromosomal abnormalities (6 cases), klinefelter syndrome (4 cases) and Turner syndrome (17 cases) genetically confirmed, collected at endocrinology service at Sfax University Hospi...

IntroductionHypopituitarism is a rare condition defined by loss of pituitary function due to involvement of hypothalamus and/or pituitary gland by infiltrative diseases mainly sarcoidosis and Langerhans cell histiocytosis (LCH). Central diabetes insipidus is the most frequent manifestation of LCH (10–50%) and rarely in neuro-sarcoidois. Herein, we describe 2cases of hypopituitarism due to neuro-sarcoidosis and LCH.Case 1<p...